Sebaceous carcinoma of the nose with a regional metastasis following false-negative sentinel lymph node biopsy.

A recent large-scale retrospective study has revealed that the frequency and aggressiveness of extraocular sebaceous carcinoma is comparable with that of the periocular counterpart (1) and a signiflcant number of extraocular sebaceous carcinomas show regional and widespread métastases (2). However, sentinel lymph node (SLN) biopsy has seldom been used for identifying regional nodal metastasis in extraocular sebaceous carcinoma. We report here the case of a nasal sebaceous carcinoma which was excised in combination with SLN biopsies showing no tumour cells. However, 6 months after surgery, a metastasis to the submental lymph node was detected. The efticacy of SLN biopsy in extraocular sebaceous carcinoma is discussed.